MOTS-c Dosage Calculator & Chart
Printed on the vial label.
1 mg = 1,000 mcg. Enter your own prescribed or planned amount.
Draw on your syringe
100units= 1 mL
- Concentration
- 5,000mcg/mL
- Each unit
- 50 mcg
- Doses per vial
- 2
- Vial lasts
- 2days
Want a rounder number to draw?
Show the math
- Concentration = 10 mg × 1,000 ÷ 2 mL = 5,000 mcg/mL
- Volume = 5,000 mcg ÷ 5,000 mcg/mL = 1 mL
- Units = 1 mL × 100 = 100 units (U-100: 100 units = 1 mL)
The pre-filled dose (5 mg) is an example input so the calculator shows a result. It is not a recommendation.
MOTS-c dosage chart (in units)
No validated human dose.
MOTS-c has not been approved for human use, and there are no controlled human trials that establish a dose. The amounts below are what public protocol websites report — they are shown so you can see how they translate into syringe units, not as a recommendation.
Online protocols list about 5 mg per week, given as one 5 mg injection or split into 2.5 mg twice weekly. Units are calculated for your current mix (10 mg vial + 2 mL water).
| Reported as | Amount | Frequency reported | Units (U-100) | mL |
|---|---|---|---|---|
| Single weekly injection | 5 mg | 1× weekly | 100 | 1 |
| Split dose | 2.5 mg | 2× weekly | 50 | 0.5 |
Reported by: Path to Peptides — MOTS-c protocol guide (community protocol site); PeptideCalcs — MOTS-c calculator (community reference site). Read 2026-10-10.
MOTS-c units chart
Units to draw on a U-100 syringe for common MOTS-c vial sizes, each mixed with 2 mL of bacteriostatic water. Change the water in the calculator and this table updates.
| Dose | 5 mg vial | 10 mg vial | 40 mg vial |
|---|---|---|---|
| 1 mg | 40 | 20 | 5 |
| 2.5 mg | 100 | 50 | 12.5 |
| 5 mg | >100 | 100 | 25 |
| 10 mg | >100 | >100 | 50 |
Values are units on a U-100 insulin syringe (100 units = 1 mL). ">100" means the dose does not fit in a 1 mL syringe at this dilution.
About MOTS-c
MOTS-c is a 16-amino-acid peptide encoded in mitochondrial DNA, studied mainly in animals for its effects on metabolism.
Regulatory status: Not approved by the FDA for any human use. Products sold as "research peptides" are not regulated as medicines, and their purity and labeled content are not verified.
Also searched as: MOTS c, MOTSc.
How to reconstitute MOTS-c
- Wash your hands and let the vial reach room temperature.
- Wipe the rubber stoppers of the peptide vial and the bacteriostatic water with an alcohol pad.
- Draw the planned amount of bacteriostatic water (for example 2 mL — that is 200 units on a 1 mL syringe).
- Inject the water slowly down the inside wall of the vial, not directly onto the powder.
- Gently swirl or roll the vial until the powder dissolves. Do not shake.
- Label the vial with the date and the concentration shown by the calculator, and store it as the product label directs (reconstituted peptides are normally kept refrigerated).
These are general handling steps, not medical instructions. If your product came with instructions from a pharmacy or prescriber, follow those.
What you need
Bacteriostatic water
Sterile water with 0.9% benzyl alcohol, used to dissolve the powder.
U-100 insulin syringes
0.3 mL syringes are easiest to read for small doses; 1 mL for larger ones.
Alcohol prep pads
Wipe the vial stopper before every draw.
Sharps container
For safe disposal of used needles.
- Which syringes and supplies to buy →
MOTS-c calculator FAQ
How many units is 5 mg of MOTS-c?
+
It depends on how much water you add. With a 10 mg vial mixed with 2 mL of bacteriostatic water, the concentration is 5,000 mcg/mL, so 5 mg is 1 mL = 100 units on a U-100 insulin syringe. With a 40 mg vial and the same 2 mL of water it is 25 units.
How much water should I add to a 10 mg MOTS-c vial?
+
The water volume does not change the total amount of MOTS-c; it only sets the concentration. Common choices are 1–3 mL. With 2 mL, each unit on a U-100 syringe holds 50 mcg. Pick a volume that makes your dose easy to read on the syringe — the calculator above suggests volumes that land on round numbers.
How many doses are in a 10 mg vial of MOTS-c?
+
At 5 mg per injection, a 10 mg vial contains 2 full doses. The amount of water you add does not change this number.
What MOTS-c dosage do people use?
+
There is no validated human dose for MOTS-c. Online protocols list about 5 mg per week, given as one 5 mg injection or split into 2.5 mg twice weekly. For reference, 5 mg from a 10 mg vial mixed with 2 mL of water is 100 units. These figures come from protocol websites, not clinical trials, and are not a recommendation.
Is MOTS-c approved?
+
Not approved by the FDA for any human use. Products sold as "research peptides" are not regulated as medicines, and their purity and labeled content are not verified.
Sources
- Lee C et al. The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance. Cell Metab. 2015;21(3):443-454.
- Path to Peptides — MOTS-c protocol guide (community protocol site)
- PeptideCalcs — MOTS-c calculator (community reference site)
Calculator math: concentration = vial mg × 1,000 ÷ water mL; units = dose ÷ concentration × 100 (U-100 syringe). Data and references last reviewed 2026-10-10.