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FDA-approved drugSexual & reproductive

PT-141 Dosage Calculator & Chart

Work out exactly how many units of PT-141 to draw on a U-100 insulin syringe. Pre-filled with a 10 mg vial and 2 mL of bacteriostatic water — change any value to match your vial.
mg

Printed on the vial label.

mL
Dose per injection
mg

1 mg = 1,000 mcg. Enter your own prescribed or planned amount.

Syringe size (U-100)

Draw on your syringe

35units= 0.35 mL

Nearest mark on a 1 mL syringe: 36 units (≈ 1.8 mg)

010203040506070809010035 units1 mL · U-100 · 100 units
Concentration
5,000mcg/mL
Each unit
50 mcg
Doses per vial
5
Vial lasts
5days

Want a rounder number to draw?

Show the math
  1. Concentration = 10 mg × 1,000 ÷ 2 mL = 5,000 mcg/mL
  2. Volume = 1,750 mcg ÷ 5,000 mcg/mL = 0.35 mL
  3. Units = 0.35 mL × 100 = 35 units (U-100: 100 units = 1 mL)

The pre-filled dose (1.75 mg) is an example input so the calculator shows a result. It is not a recommendation.

PT-141 dosage chart (in units)

Units to draw for each dose at your current mix (10 mg vial + 2 mL water). Vyleesi prescribing information: 1.75 mg injected under the skin at least 45 minutes before anticipated sexual activity; no more than one dose in 24 hours and no more than 8 doses per month.

PeriodDoseUnits (U-100)mL
As needed (label dose)1.75 mg350.35

PT-141 units chart

Units to draw on a U-100 syringe for common PT-141 vial sizes, each mixed with 2 mL of bacteriostatic water. Change the water in the calculator and this table updates.

Dose10 mg vial
500 mcg10
1 mg20
1.75 mg35
2 mg40

Values are units on a U-100 insulin syringe (100 units = 1 mL). ">100" means the dose does not fit in a 1 mL syringe at this dilution.

About PT-141

PT-141 (bremelanotide) is a melanocortin receptor agonist. It is FDA-approved as Vyleesi, an as-needed injection for acquired, generalized hypoactive sexual desire disorder in premenopausal women.

Regulatory status: FDA-approved as Vyleesi (autoinjector) for a specific indication. Use only as prescribed. Vials sold as "PT-141 research peptide" are not FDA-approved products.

Also searched as: bremelanotide, Vyleesi, PT 141.

How to reconstitute PT-141

  1. Wash your hands and let the vial reach room temperature.
  2. Wipe the rubber stoppers of the peptide vial and the bacteriostatic water with an alcohol pad.
  3. Draw the planned amount of bacteriostatic water (for example 2 mL — that is 200 units on a 1 mL syringe).
  4. Inject the water slowly down the inside wall of the vial, not directly onto the powder.
  5. Gently swirl or roll the vial until the powder dissolves. Do not shake.
  6. Label the vial with the date and the concentration shown by the calculator, and store it as the product label directs (reconstituted peptides are normally kept refrigerated).

These are general handling steps, not medical instructions. If your product came with instructions from a pharmacy or prescriber, follow those.

What you need

  • Bacteriostatic water

    Sterile water with 0.9% benzyl alcohol, used to dissolve the powder.

  • U-100 insulin syringes

    0.3 mL syringes are easiest to read for small doses; 1 mL for larger ones.

  • Alcohol prep pads

    Wipe the vial stopper before every draw.

  • Sharps container

    For safe disposal of used needles.

  • Which syringes and supplies to buy →

PT-141 calculator FAQ

How many units is 1.75 mg of PT-141?

+

It depends on how much water you add. With a 10 mg vial mixed with 2 mL of bacteriostatic water, the concentration is 5,000 mcg/mL, so 1.75 mg is 0.35 mL = 35 units on a U-100 insulin syringe.

How much water should I add to a 10 mg PT-141 vial?

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The water volume does not change the total amount of PT-141; it only sets the concentration. Common choices are 1–3 mL. With 2 mL, each unit on a U-100 syringe holds 50 mcg. Pick a volume that makes your dose easy to read on the syringe — the calculator above suggests volumes that land on round numbers.

How many doses are in a 10 mg vial of PT-141?

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At 1.75 mg per injection, a 10 mg vial contains 5 full doses. The amount of water you add does not change this number.

What is the PT-141 dosage schedule?

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Vyleesi prescribing information: 1.75 mg injected under the skin at least 45 minutes before anticipated sexual activity; no more than one dose in 24 hours and no more than 8 doses per month. The dosage chart above converts each step into units for your vial. Follow your prescriber's instructions.

Is PT-141 approved?

+

FDA-approved as Vyleesi (autoinjector) for a specific indication. Use only as prescribed. Vials sold as "PT-141 research peptide" are not FDA-approved products.

Sources

  1. Vyleesi (bremelanotide) prescribing information — DailyMed

Calculator math: concentration = vial mg × 1,000 ÷ water mL; units = dose ÷ concentration × 100 (U-100 syringe). Data and references last reviewed 2026-10-10.

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